Using thousands of AI agents to uncover new leads in biological data openai.com

OpenAI, PerturbAI and Scripps Research used thousands of GPT-Rosalind agents to analyze a mouse-brain CRISPR dataset covering millions of cells in 32 minutes, connecting gene disruptions with scientific literature. The analysis surfaced leads including differing effects of Tsc1 and Tsc2 disruptions in cerebellar neurons and a possible link between DCTN1, cholesterol regulation and neurodegeneration; blinded experts preferred distributed-agent reports to single-agent reports 75% of the time.