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Malaria Parasite Caught in the Act of Breaking and Entering quantamagazine.org
Researchers including Caroline Ho’s team mapped the malaria parasite’s “moving junction,” the structure it uses to enter red blood cells, identifying a potential point for blocking infection. Their AI-designed inhibitory protein stopped Plasmodium invasion in test tubes, but has not yet been tested in animals; the brief invasion process may make it a difficult drug target.